Mobocertinib succinate,CAS#2389149-74-8
CAS No. 2389149-74-8 Cat. No. BCP33315
Name Mobocertinib succinate
Synonyms TAK-788 succinate; AP32788 succinate;TAK 788 succinate; AP 32788 succinate;TAK788 succinate; AP-32788 succinate;


Chemical Name
Formula C36H45N7O8 M. Wt 703.78
Purity 98% Storage Store at 4-8°C
Description Mobocertinib succinate is a potent and orally active inhibitor of EGFR and HER2 oncogenic mutants, including exon 20 insertions, with selectivity over WT EGFR. Antitumor activity.Mobocertinib, also known as TAK-788 and AP32788, is an investigational TKI with potent, selective preclinical activity against activating EGFR and HER2 mutations, including exon 20 insertions. TAK-788 exhibits antitumor activity in pts with EGFR exon 20 insertions with an AE profile consistent with other EGFR TKIs.